Discussion
Diagnosis With Brief Discussion
- Diagnosis
- Chronic eosinophilic pneumonia
- Radiologic Findings
- Initial chest PA showed bilateral patchy or peripheral consolidations and GGOs in the both lung fields.
Chest CT showed multifocal, patchy consolidations with internal air bronchograms and surrounding GGOs in the entire lung fields. Lesions were more peripheral with upper lobar predominance. Our differential diagnosis was chronic eosinophilic pneumonia, cryptogenic organizing pneumonia, and Churg-Strauss syndrome.
VATS wedge resection was done in the right lower lobe. Pathologic findings were acute and chronic inflammation with eosinophilic infiltration in the interstitium and intraalveolar areas with fibrosis.
Steroid treatment was started and then taken FU CXR after 3months shows almost regression.
- Brief Review
- CEP is an idiopathic condition characterized by chronic and progressive clinical features and an abnormal, marked accumulation of eosinophils in the interstitium and alveolar spaces of the lung. The clinical manifestation is usually insidious, and the patient experiences symptoms for an average of 7.7 months before the diagnosis is made. Most patients are middle aged, and approximately 50% have asthma. Women are more frequently affected than men. Pulmonary function tests can be normal in mild cases but usually show restrictive defects.
The typical chest radiographic finding in CEP is nonsegmental peripheral airspace consolidation (photographic negative shadow of pulmonary edema) involving mainly the upper lobes.
CT demonstrates typical nonsegmental areas of airspace consolidation
with peripheral predominance. Less common findings include ground-glass
opacities, nodules, and reticulation. CT performed more than 2months after the onset of symptoms shows linear band-like opacities parallel to the pleural surface, whereas in Cryptogenic organizing pneumonia(COP), consolidation involving subpleural and peribronchial areas was the most common finding with somewhat lower lobar dominancy. Also, bronchial dilatation within the consolidative or GGO lesion was seen significantly more often in COP than in CEP.
- Please refer to
Case 163, Case 281, Case 323, Case 369, Case 806, Case 1064, Case 1085, -
KSTR Symposium 1999 Case 3
,
KSTR Imaging Conference 2016 Spring Case 12
,
KSTR imaging conference 2018 Spring Case 7,
- References
- 1) Adam Bernheim, Theresa McLoud. A Review of Clinical and Imaging Findings in Eosinophilic Lung Diseases. AJR 2017; 208:1002
- Keywords
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